Malignant Smooth Muscle Tumor of Broad Ligament: A Rare Diagnostic Challenge
Faridah Shamsudin *
Gynecologic-Oncology Unit, Hospital Raja Permaisuri Bainun, Ipoh, Malaysia.
Lee Saw Joo
Gynecologic-Oncology Unit, Hospital Raja Permaisuri Bainun, Ipoh, Malaysia.
Naerenthini Ganabathy
Gynecologic-Oncology Unit, Hospital Raja Permaisuri Bainun, Ipoh, Malaysia.
Anusha Kalyanasundaram
Pathology Department, Hospital Raja Permaisuri Bainun, Ipoh, Malaysia.
*Author to whom correspondence should be addressed.
Abstract
Leiomyosarcoma (LMS) represent a minority of uterine malignancies, comprising merely 1-2% of the total cases. Those of the broad ligament are very rare, rapidly progressive and highly malignant gynecological tumor.
Because of its rarity and atypical localization, we present a case of a young woman 38 years old which initially mimicked an ovarian malignancy and was complicated by multi-organ involvement at presentation. She underwent Total Abdominal Hysterectomy + Bilateral Salphingoophorectomy + Resection of left broad ligament tumor, in which histopathological diagnosis prove as myxoid type of leiomyosarcoma of the left broad ligament. She received total 6 cycle of adjuvant chemotherapy (Cisplatin + Doxorubicin) followed by adjuvant radiotherapy (45Gy/25 fraction) of external beam radiotherapy.
Keywords: Leiomyosarcoma, uterine malignancies, uterine sarcomas, muscle tumor