Can Red Cell Distribution Width (RDW) and Platelet Indices Predict the Severity of Pre-eclampsia?
Published: 2021-05-05
Page: 69-73
Issue: 2021 - Volume 4 [Issue 1]
Deepika Kashyap *
Department of Obstetrics and Gynecology, All India Institute of Medical Sciences, New Delhi, India.
Reena Yadav
Department of Obstetrics and Gynaecology, Lady Hardinge Medical College, New Delhi, India.
Smita Singh
Department of Pathology, Lady Hardinge Medical College, New Delhi, India.
*Author to whom correspondence should be addressed.
Abstract
Objective: The aim was to study the relationship between platelet indices and red cell distribution width (RDW) with pre-eclampsia and its severity.
Methods: A matched case-control hospital-based observational study was performed with 80 pre-eclamptic women and a control group of 80 normotensive women in the gestational age of 28+0 weeks - 40+6 weeks. Blood samples for routine blood count and RDW levels were analyzed.
Results: The RDW levels were significantly higher in pre-eclampsia group compared to the control group. We also confirmed that the RDW levels were significantly higher in women with severe pre-eclampsia as compared to women with non severe pre-eclampsia on subgroup analysis.
Conclusion: There is a statistically significant association between the RDW and risk of pre-eclampsia and also its severity. It is a marker which is easy to use, inexpensive and can be calculated as a part of routine blood count. It has significant prognostic value in patients with pre-eclampsia.
Keywords: Pregnancy, pre-eclampsia, platelet indices, red cell distribution width